STUDYING THE CELLULAR BASIS OF SMALL BOWEL ENTEROPATHY USING HIGH-PARAMETER FLOW CYTOMETRY IN MOUSE MODELS OF PRIMARY ANTIBODY DEFICIENCY

Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency

BackgroundPrimary immunodeficiencies are heritable defects in immune system function.Antibody deficiency is the most common form of primary immunodeficiency in humans, can be caused by abnormalities in Puzzles New/Sealed both the development and activation of B cells, and may result from B-cell-intrinsic defects or defective responses by other cell

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The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

LIM-domain only protein 4 (LMO4) is a widely expressed protein with important roles in embryonic development and breast cancer.It has been reported to bind many partners, including the transcription factor Deformed epidermal autoregulatory factor-1 (DEAF1), with which LMO4 shares many biological parallels.We used yeast two-hybrid assays to show tha

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What do people think about technological enhancements of human beings? An introductory study using the Technological Enhancements Questionnaire in the context of values, the scientistic worldview, and the accepted versions of humanism

Introduction Rapid development of technologies increases the possibility of technological enhancements of human beings, e.g., in their cognitive skills or physical fitness.Attitudes towards such enhancements may result in their social acceptance or rejection.Material and methods One hundred and thirty-nine young Polish adults participated in the st

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Analysis of Material Supplier Selection in Laminated Bamboo Shipyards Using the Analytical Hierarchy Process Method

The material supply chain is an essential part of the shipbuilding industry.For this reason, it is necessary to select suppliers who can support the material needs of ship production.Qualitative and quantitative factors are multi-criteria problems in supplier selection.The Analytical Hierarchy Process (AHP) method effectively determines an integrat

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